BDBM50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE

SMILES COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O

InChI Key InChIKey=XMXHEBAFVSFQEX-UHFFFAOYSA-N

Data  55 KI  12 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034043   

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50034043(1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...)Copy SMILESCopy InChI

Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
PC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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